NEW YORK (AP) — The latest on developments in financial markets (All times local):

4:05 p.m.

Stocks are closing sharply lower on Wall Street as technology and industrial firms as well as banks take sharp losses amid weak quarterly earnings.

Chipmaker Advanced Micro Devices sank 13.4 percent Wednesday and network equipment maker Juniper Networks fell 6.1 percent as their fourth-quarter forecasts disappointed investors.

Media and marketing information company Nielsen fell 6.3 percent after its third-quarter report and railroad operator Norfolk Southern sank 2.7 percent.

Bond prices fell. The yield on the 10-year Treasury note rose to 2.43 percent and reached a seven-month high.

The Standard & Poor's 500 index lost 12 points, or 0.5 percent, to 2,557.

The Dow Jones industrial average shed 112 points, or 0.5 percent, to 23,329. The Nasdaq composite lost 35 points, or 0.5 percent, to 6,564.

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12:05 p.m.

Stocks are falling in midday trading as technology and industrial firms as well as banks take sharp losses amid weak quarterly earnings.

Chipmaker Advanced Micro Devices sank 11.9 percent Wednesday and network equipment maker Juniper Networks fell 6.8 percent as their fourth-quarter forecasts disappointed investors.

Media and marketing information company Nielsen fell 5.2 percent after its third-quarter report and railroad operator Norfolk Southern sank 1.5 percent.

Chipotle Mexican Grill tumbled 15 percent after its results came up short of investors' expectations.

The Standard & Poor's 500 index lost 20 points, or 0.8 percent, to 2,550.

The Dow Jones industrial average shed 135 points, or 0.6 percent, to 23,312. The Nasdaq composite lost 62 points, or 1 percent, to 6,536.

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9:40 a.m.

Stocks are starting the day lower as industrial companies take modest losses.

Media and marketing information company Nielsen fell 5.2 percent Wednesday after its third-quarter report. Railroad operator Norfolk Southern sank 1.5 percent.

Banks rose with interest rates. The yield on the 10-year Treasury note climbed to 2.45 percent.

The Commerce Department said orders for long-lasting manufactured goods rose in September. A figure that tracks business investment grew for the third month in a row.

Chipotle Mexican Grill tumbled 13.7 percent after reporting disappointing third-quarter results.

The Standard & Poor's 500 index lost 2 points, or 0.1 percent, to 2,566.

The Dow Jones industrial average shed 6 points to 23,435. The Nasdaq composite was little changed at 6,597.