CINCINNATI (AP) — Johnny Cueto pitched his third career shutout against the team that beat him in the playoffs, and Joey Votto hit a two-run homer that led the Cincinnati Reds over the Pittsburgh Pirates 4-0 Wednesday for their first winning series this season.

Cueto (1-2) had his way with the lineup that beat him 6-2 in the NL wild card playoff at PNC Park last year. He limited the Pirates to three hits and struck out a career-high 12 during his first shutout since 2011.

Several Pirates questioned called third strikes by Quinn Wolcott, a Triple-A umpire called up to the majors. Eight of Cueto's strikeouts were called.

After the NL Central rivals combined for 13 homers while splitting the first two games, Votto supplied the one that broke open the deciding game.

Left-hander Francisco Liriano (0-3) opened the game by walking Billy Hamilton, who stole second base and came around on two wild pitches. That was it for scoring until the seventh inning, when Cueto singled and Votto hit his fourth homer in six games. Brayan Pena doubled home a run in the eighth.

Liriano and Cueto also were matched in the wild card game last season. Liriano got the better of that one, going seven innings for the victory while Cueto failed to make it through the fourth at PNC Park.

Liriano had trouble at the outset on Wednesday. Ten of his first 13 pitches were balls. He walked Hamilton and Votto opening the inning, then threw the two wild pitches that let in the run.

Cueto started only 11 games last season because of stained muscles by his pitching shoulder. The right-hander has been solid this season but hasn't gotten much help from an offense that scored only one run while he was on the mound during his first three starts.

The Ohio River rivals had a bruising series last season, with 28 batters hit overall — the most for any series in the majors. It's been mostly pain-free so far, with only two batters hit during the series.

Pirates left fielder Jose Tabata left the game in the fifth inning with what appeared to be a mild concussion after he slammed into the outfield wall while catching Pena's fly ball. Tabata fell, held up his glove to show he'd caught the ball and sat on the warning track for several minutes.

A trainer examined Tabata's neck, jaw and head, and he was helped off the field.

NOTES: The Pirates completed their first trip of the season at 3-6. They open a four-game series against Milwaukee on Thursday, with Edinson Volquez starting against Yovani Gallardo. ... The Reds concluded a 3-3 homestand. They're off on Thursday before opening a 10-game trip at Wrigley Field. Alfredo Simon starts against the Cubs' Jeff Samardzija. ... Reds closer Aroldis Chapman is to throw in the bullpen for the second time on Thursday. The Reds are hoping to have him back from a head injury next month. ... Cueto was called for interference twice while trying to bunt. The first time, he ran out of the box to bunt the ball. The second time, he stood in the box and blocked catcher Tony Sanchez from fielding the bunt.

___

Follow Joe Kay on Twitter: http://twitter.com/apjoekay