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September 5, 2008 8:28:27 PM CDT

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Gene Therapy for Parkinson's Delivers Major Results

Posted Nov 20, 07 4:47 AM CST in Technology,  Science & Health 

(Newser) – New evidence indicates that the first gene therapy for Parkinson's disease has achieved measurable success. Brain scans of patients receiving the treatment confirmed significant changes, supporting earlier anecdotal accounts of 65% improvements in mobility and other gains, according to a study published in the Proceedings of the National Academy of Sciences.

Doctors participating in the study injected a virus modified with human DNA into one side of the patients' brains, leaving the other untreated to serve as a control. The therapy boosted levels of a chemical that calms overexcited brain cells in the treated side of the brain, while the untreated side showed no change. "It is the first solid evidence of benefit from gene therapy," said one researcher.

Source Daily Telegraph (UK)

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Actor Michael J. Fox, who is afflicted with Parkinson's Disease, gestures during an address to the Bio International Convention in Boston, Monday, May 7, 2007. Fox appealed to scientists and investors...   (Associated Press)
Surgeons prepare to operate on a man with Parkinson's disease. (AP Photo/Adil al-Khazali)   (Associated Press)
The first dozen Parkinson's patients to have holes drilled in their skulls for a novel gene therapy attempt weren't harmed _ and hints at some improvement have researchers embarking on a larger study...   (Associated Press)
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genetics  • medical breakthrough  • brain  • Parkinson's disease  • gene therapy


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