1 in 10 Americans on Antidepressants Use is up 400% since 1988, says CDC By John Johnson, Newser Staff Posted Oct 20, 2011 4:39 PM CDT 32 comments Comments File photo of antidepressant pills. (Getty Images) (Newser) – The CDC rounds up some depressing stats about antidepressant use: More than one in 10 Americans (11%) older than 12 take the drugs, the majority of them for depression. That marks a 400% increase since 1988 and makes antidepressants the most commonly used drug for people ages 18 to 44, notes USA Today. Less than one-third of those on antidepressants have seen a mental health professional in the last year. Women are more likely than men to take the drugs, and 23% of females ages 40 to 59 do so. About 14% of whites take antidepressants, versus 4% of blacks and 3% of Mexican-Americans, notes the Wall Street Journal. More than 60% of those on the medication have been taking it for more than two years. Only about one-third of people with symptoms of severe depression are taking them.