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October 12, 2008 3:29:55 PM CDT

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New Key to Breast Cancer Discovered

Posted Dec 10, 07 4:57 AM CST in Science & Health 

(Newser) – Scientists believe they've made a breakthrough discovery in why a certain genetic mutation can cause a particularly deadly form of breast cancer. Mutations in the BRCA1 gene are apparently linked to the loss of an important protein, PTEN, that checks cell growth, according to a new study in the journal Nature.

Between 50% and 85% of women with a BRCA1 mutation will develop breast cancer, accounting for up to 10% of breast cancer cases. The so-called "triple-negative" type of cancer linked to the gene doesn't respond well to current treatments. Scientists hope this finding will lead to new treatments.

Sources Reuters, Daily Telegraph (UK)

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Nancy Hayes, 43, left, undergoes a digital mammogram as Beaumont radiologic technician Shayrn Schymick takes notes.   (KRT Photos)
  (Magnum Photos)
Dr. Murray Rebner reviews a mammogram done using digital technology at Beaumont Hospital in Michigan.   (KRT Photos)
  (Associated Press)
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breast cancer  • genetic mutation  • tumors  • BRCA1


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