Soy Sauce Molecule Could Treat HIV—Better
Soy sauce company's 2001 discovery holds
By Kate Seamons, Newser Staff
Posted May 7, 2014 7:36 AM CDT
   (Shutterstock)

(Newser) – Picture the soy sauce bottle on most sushi restaurant tables, yep, the one with the red or green top. Those omnipresent bottles are the product of the Yamasa Corporation, which started manufacturing the soy sauce in 1645. But the most fascinating part of the Japan company's history is a thoroughly recent one: Virologists have confirmed that Yamasa's scientists did indeed make a discovery involving a molecule related to flavor enhancers contained in soy sauce—and HIV. Vocativ reports that Yamasa in 1988 established a division of food scientists who were tasked with carrying out research on how the immune system responds to a variety of chemicals in food; in 2001, they announced a big find: that the molecule, EFdA, could possibly be used in treatment of HIV.

That's because EFdA, along with eight HIV drugs on the market, belongs to a family of compounds that help prevent HIV replication, explains the University of Missouri, whose virologists researched Yamasa's findings and this week confirmed them. But the issue with some of those drugs—the researchers single out the commonly used Tenofovir—is that patients develop resistance to them and then need to step up to a more powerful drug. But as Missouri researcher Stefan Sarafianos found, EFdA "is less likely to cause resistance" because it's activated more readily and doesn't break down in the liver and kidneys as rapidly as similar drugs. His lab has discovered it "works 10 times better than on wild-type HIV that hasn’t become Tenofovir resistant" and it works even better—70 times better—on HIV that has grown resistant to Tenofovir. Sarafianos has teamed up with Merck to test potential new drugs. (Read about another unusual medical discovery involving mice.)

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Jeffrey Dowling
Mar 22, 2015 8:27 AM CDT
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Jeffrey Dowling
Mar 22, 2015 8:27 AM CDT
Hello, Every one Here i was diagnosed with HIV/AIDS for over 5 years which made loose my job and my relationship with my fiance after he discovered that i was having HIV, he departed from me i tried all my best to make him stays with me, but neglected me until a friend of mine on Facebook from Singapore told me Great healer, who will restore my life back with his powerful healing spell, he sent me the email address to contact and i quickly contacted him, and he said my condition can solved, that he will treat the disease immediately only if i can accept trust him and accept his terms and condition, i Agreed because i was so much in need of help by all means, so i did all he want from me and surprisingly on Sunday last week He sent me a text, that i should hurry up to the hospital for a checkup, which i truly did, i confirm from my doctor that i am now ( HIV NEGATIVE) my eyes filled with tears and joy, crying heavily because truly the disease deprived me of many things from my life, This is a Miracle, Please do not en-devour to email dr.apetorkushrine@gmail.com or dr.apetorkushrine@hotmail.com for healing and solution or website: http://drapetorkushrine.webs.com/........
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Nov 19, 2014 8:30 AM CST
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