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Hormone Therapy Skews Diagnosis

Drugs increase false mammogram results, unnecessary biopsies

By Zach Samalin,  Newser Staff

Posted Feb 26, 2008 11:55 AM CST

(Newser) – Women who use hormone replacement therapy to combat menopause symptoms are more likely to get false mammogram results and have unneeded biopsies, new research shows. The UCLA analysis of an earlier study of more than 16,000 women found that 35% of those on hormones received skewed test results, as opposed to 23% of women on a placebo, Reuters reports.

Hormone treatment not only produces more false positives, it interferes with detection of malignancies in mammograms and biopsies, researchers found. "This is really definitive evidence that hormones interfere with breast cancer diagnosis," a researcher told the San Francisco Chronicle. One in 1,000 hormone replacement patients will get breast cancer, one in 10 will get an abnormal mammogram, and one in 25 will have an avoidable biopsy, she said.

The MAMMOMAT(R) Novation S digital mammography system from Siemens Medical Solutions is designed to optimize clinical workflow for screenings. The system provides a cost-effective solution for facilities that are making the transition to digital breast imaging but do not have the need for advanced diagnostic functionality. The MAMMOMAT Novation S...
The MAMMOMAT(R) Novation S digital mammography system from Siemens Medical Solutions is designed to optimize clinical workflow for screenings. The system provides a cost-effective solution for facilities...   (Associated Press)
A good mammogram reader may do just as well at spotting cancers without expensive new computer systems often used for a second opinion, a new study suggests. Computerized mammography, now used for about a third of the nation's mammograms, too often finds harmless spots that lead to false scares, researchers...
A good mammogram reader may do just as well at spotting cancers without expensive new computer systems often used for a second opinion, a new study suggests. Computerized mammography, now used for about...   (Associated Press)
Dr. Murray Rebner reviews a mammogram done using digital technology at Beaumont Hospital in Michigan.
Dr. Murray Rebner reviews a mammogram done using digital technology at Beaumont Hospital in Michigan.   (KRT Photos)
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