11 Least Religious Cities in the US Yup, Sin City makes the list By Evann Gastaldo, Newser Staff Posted Feb 1, 2016 12:11 PM CST 122 comments Comments The San Francisco skyline is visible at sunrise on Jan. 7, 2016, in this view from Sausalito, Calif. (AP Photo/Eric Risberg) (Newser) – Haven't yet found God and don't plan to? You might feel right at home in Portland, San Francisco, or Seattle. Those are the least religious cities in the country, according to a new survey from the Public Religion Research Institute picked up by MarketWatch. Here are the 11 least religious US cities, along with the percentage of unaffiliated residents in each one: Portland, Ore. (tie): 37% San Francisco, Calif. (tied for first): 37% Seattle, Wash. (tied for first): 37% Denver, Colo. (tie): 29% Las Vegas, Nev. (tied for 4th): 29% Minneapolis-St. Paul, Minn.: 28% Columbus, Ohio: 27% Boston, Mass. (tie): 26% Washington, DC (tied for 8th): 26% Cincinnati, Ohio (tie): 25% Detroit, Mich. (tied for 10th): 25% Complete list here.