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July 5, 2008 5:08:25 PM CDT



Gene Breakthrough Aids Blind

Posted Apr 28, 08 2:42 AM CDT in Science & Health    Most Covered

(Newser) – A rare and incurable congenital disease which causes blindness has been successfully treated for the first time using gene therapy, Reuters reports. Doctors inserted a healthy gene directly into one eye of patients suffering from Leber congenital amaurosis using a genetically engineered cold virus. Patients reported an improvement in their eyesight even though none was expected.  

The disease damages light receptors in the retina and usually causes total blindness by the age of 30. "This result is important for the entire field of gene therapy," said the lead researcher of one of the studies published in the New England Journal of Medicine. Genetic research to treat illness suffered serious setbacks in recent years when some experiments went awry.

Source Reuters

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A patient undergoing a PET scan after gene therapy at the Hospital of the University of Pennsylvania in Philadelphia. Doctors at the hospital report a breakthrough impacting the whole field.   (KRT Photos)
Steven Howarth, 18, playing guitar at his home in Bolton, England. He is one of several blind patients experimentally treated with gene therapy.   (AP Photo/BBC)
Dr. Albert Maguire and wife Dr. Jean Bennett at the University of Pennsylvania. The two are among two teams of scientists using gene therapy to treat blind patients.   (AP Photo)
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