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Combo Heart Pills Enter Trials in London

The cheap drugs could halve deaths from heart attack, stroke

By Matt Cantor,  Newser Staff

Posted Sep 29, 2008 8:16 AM CDT

(Newser) – Trials begin this week in London on a cheap "polypill" that could cut heart attack and stroke deaths in half worldwide, the Guardian reports. The pill combines four drugs—aspirin, a cholesterol-lowering statin, an ACE inhibitor, and thiazine to battle high blood pressure. The aim is to sell it—for about $1 a month—over the counter at pharmacies in the developing world, where cardiovascular disease is soaring.

Funding the long-envisioned polypill has been difficult because it offers little opportunity for drug-company profit. “We spent a few years trying to persuade a number of companies to do this, but got nowhere. A pill with established medicines that halved cardiovascular risk and could be available for £20 a year could be seen as a threat,” said a researcher. The so-called Red Heart pill has been manufactured by an Indian drug company for the two UK organizations backing the trials.

It has been difficult to find funding for research into the cheap pills.
It has been difficult to find funding for research into the cheap pills.   (Shutterstock)
Inexpensive pills are entering London trials.
Inexpensive pills are entering London trials.   (Shutterstock)
The pills combine four drugs, including aspirin.
The pills combine four drugs, including aspirin.   (Shutterstock)
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Seventeen million people die of heart disease and strokes every year and 80% of deaths are in developing countries. Polypill enthusiasts say the death toll could be halved by the daily Red Heart tablet, which would cost $1 a month.

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