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SATURDAY, NOVEMBER 21, 2009
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4

South Koreans Clone Beagles—and They Glow

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(Newser) – South Korean scientists have cloned a group of four female beagles that glow red under ultraviolet light, the AP reports. The researchers inserted fluorescent genes during the cloning process, an achievement that could lead to advances in human medicine and science. “What’s significant in this work is not the dogs expressing red colors,” the lead researcher said, “but that we planted genes into them.”

The scientists have already started implanting disease-related genes during the cloning process, and hope the research could lead to therapies for maladies such as Parkinson’s. “This is a step forward,” a watcher said. “What is important now is on what specific diseases the team will focus on.” The beagles are the first dogs cloned with fluorescent genes, though the process has been completed with mice and pigs.

One of the dogs shortly after birth.
One of the dogs shortly after birth.   (AP Photo)
A photo of one of the dogs under ultraviolet light.
A photo of one of the dogs under ultraviolet light.   (AP Photo)
The world's first transgenic female dogs carrying fluorescent genes.
The world's first transgenic female dogs carrying fluorescent genes.   (AP Photo)
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Doctor_Zaius
Apr 28, 09 3:58 PM CDT
When the lead scientist was pressed for further comments he stated “Not only do they glow red but they taste delicious!” Reply
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morenogabr
Apr 28, 09 4:19 PM CDT
haha, funny Doc. I dont know how necessary this kind of project is. I think this was done more for fun or to get the public to realize the implications. We've known about glowing genes- GFP- for a while. I worked in a lab 3 yrs ago when I was a junior in HS doing this to cancer promoting genes. Its a relatively old technique that is fairly unsophisticated, so much so that a high school kid with one year of biology was allowed to perfprm this technique unsupervised. I think it is also part of AP Biology curricula in high schools. A powerful tool though! Reply
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Zorro
Apr 28, 09 8:20 PM CDT
Wow - just amazing how advanced HS studies are these days (yes, I'm a little older).
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Rob
Apr 29, 09 7:46 AM CDT
This isn’t about demonstrating fluorescent genes. It's about performing gene therapy on different organisms and fluorescent genes are just markers. Different organisms have different limitations and requirements. It’s why these techniques work in some cases and not in others. The more diverse successful ontogenetic insertions made, the better understood is the general process and usefulness of the procedure.
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