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Genetic Faults Link Manic Depression, Schizophrenia

Research slowly unravels genetic causes of mental illnesses

By Rob Quinn,  Newser Staff

Posted Jul 2, 2009 7:41 AM CDT

(Newser) – Scientists have discovered genetic variations that link schizophrenia to manic depression for the first time, the Independent reports. Research made possible by technical advances found that thousands of tiny genetic faults raised the risk of both mental illnesses, which had previously been believed to be completely distinct conditions. Experts hope the findings will lead to new and more effective treatments for both disorders.

"Our findings are a real scientific breakthrough since they tell us a lot more about the nature of the genetic risk of schizophrenia than we knew as little as a year ago," said one researcher. He cautions, however, that a huge amount of research remains to be done before the full genetic causes of schizophrenia can be pinpointed and translated into treatments.

Three wide-ranging studies have shed new light on the genetic causes of both schizophrenia and bipolar disorder.
Three wide-ranging studies have shed new light on the genetic causes of both schizophrenia and bipolar disorder.   (Shutterstock)
Three wide-ranging studies have shed new light on the genetic causes of both schizophrenia and bipolar disorder.
Three wide-ranging studies have shed new light on the genetic causes of both schizophrenia and bipolar disorder.   (Shutterstock)
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Discoveries such as these are crucial for teasing out the biology of the disease and making it possible for us to begin to develop drugs targeting the underlying causes and not just the symptoms of the disease. - Kari Stefansson, head of deCode Genetics

If some of the same genetic risks underlie schizophrenia and bipolar disorder, perhaps these disorders originate from some common vulnerability in brain development.
- Thomas Insel, director of the US National Institute for Mental Health

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COMMENTS
Showing 3 of 8 comments
Mad
Jul 3, 2009 4:55 AM CDT
Many who suffer from bipolar disorder think they are fortunate to have the mental illness they do, in fact, they call it the 'brilliant madness'
Silverbow7
Jul 2, 2009 6:50 AM CDT
I hope when they do manage to fix this, if its even possible, they do so to help these poor people not just make them easier to live with while they themselves are miserable because of the effects from the medications on them such as it is now.
Derni
Jul 2, 2009 4:31 AM CDT
Brain scans and pictures allow us to chart differences but don't rerally deal withthe functional aspect of the brain-however-Japan is close to having a brain scam that actuall gives us a picture as the brain is operating-this we help us understand the diseasxes of the brain and possible ways to correct probrlems for people confronted with these debilitating diseases.
 

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