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FRIDAY, NOVEMBER 27, 2009
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19

Scientists Cure Red-Green Color Blindness in Monkeys

Adult brain can re-wire to use new vision input: study

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(Newser) – Scientists have cured red-green color blindness in monkeys, the Times of London reports. Researchers injected a virus containing L opsin, a gene that regulates the production of the red-sensitive light receptor—known as a “cone”—into the retina of red-green colorblind adult monkeys, according to a study published in Nature. Over a 24-week period, the light sensitivity of their new cones adjusted, and the monkeys could perform well on red-green color tests.

The red-green disorder is the most common type of color blindness in humans, and L opsin deficiency is usually the reason, which suggests that the therapy used in the study could be successful in humans. Critically, the monkeys’ adult brains were able to rewire themselves to use the information from the new red cones—the researchers had expected that only young brains would be adaptable enough to respond to the treatment.

Squirrel monkeys play with dreidels, four sided spinning tops traditionally used by Jewish children during the holiday of Hanukkah, in Kfar Daniel, Israel, Monday, Dec. 22, 2008.
Squirrel monkeys play with dreidels, four sided spinning tops traditionally used by Jewish children during the holiday of Hanukkah, in Kfar Daniel, Israel, Monday, Dec. 22, 2008.   (AP Photo/Dan Balilty)
A squirrel monkeys holds a dreidel, a four sided spinning top traditionally used by Jewish children during the holiday of Hanukkah, in Kfar Daniel, Israel, Monday, Dec. 22, 2008.
A squirrel monkeys holds a dreidel, a four sided spinning top traditionally used by Jewish children during the holiday of Hanukkah, in Kfar Daniel, Israel, Monday, Dec. 22, 2008.   (AP Photo/Dan Balilty)
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Although colour blindness is only moderately life-altering, we have shown we can cure a cone disease. That is extremely encouraging for the development of therapies for human cone diseases that really are blinding.
- William Hauswirth, University of Florida

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19 comments
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Altoecko
Sep 16, 09 2:53 PM CDT
Amazing! Nature and natural biology never cease to amaze me. Reply
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+7
BlahBlahBlah
Sep 16, 09 3:02 PM CDT
Woohoo, with all of the issues plaguing the world I sure am glad we fixed that first. I get the point that it is cool research but….. really…..do something useful. Reply
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-11
IN RESPONSE:
IndependentThinker
Sep 16, 09 3:25 PM CDT
If you were red-green color blind you would be singing a different tune...
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+6
IN RESPONSE:
Realist
Sep 16, 09 3:44 PM CDT
Come on, Blah. Color-blindness is pretty common - it's a reasonable use of resources to try and cure it, especially when the treatment appears to be so straightforward. And anyway, what if you had somebody in a tight fix (like, say, Jack Bauer) who had to cut the *red* wire, because if he cut the *green* wire you'd get blown to smithereens...?
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+4
IN RESPONSE:
Unaffiliated
Sep 16, 09 5:09 PM CDT
@BlahBlahBlah A short list of important scientific discoveries that were made by accident: X-rays, vaccines, penicillin. My point is that not all research need have an immediate, practical application. Science is about going to the boundaries of what we currently know (or think we know) about the world/universe, and pushing those boundaries out a little bit. You never know what you'll find once the boundary has been moved.
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+4
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