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Brain Holds Stress-Coping Mechanism

Scientists find chemical that's key to keeping your cool—or not

By Zach Samalin,  Newser Staff

Posted Oct 21, 2007 9:38 AM CDT

(Newser) – Turns out keeping your cool really is all in your head—scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals, Reuters reports. The discovery could shed light on treatments for PTSD and depression, which are bound up with the same neurochemical produced in stressful situations.

Researchers exposed mice to a bully mouse, and then monitored the way they responded to the encounter over a period of time. Those still shaken up after a month showed disproportionately high levels of BDNF, a chemical associated with poor coping skills, found in depressed human brains. "It seems to be a signature of vulnerability to depression," said one psychologist.

Turns out keeping your cool really is all in your head%u2014scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals.
Turns out keeping your cool really is all in your head%u2014scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals.
Turns out keeping your cool really is all in your head%u2014scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals
Turns out keeping your cool really is all in your head%u2014scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals
This MRI image of a human brain shows the site of working memory - a postage stamp-sized slice of gray matter behind and above the right eye that serves as a temporary scratch-pad for conscious thou
This MRI image of a human brain shows the site of "working memory" - a postage stamp-sized slice of gray matter behind and above the right eye that serves as a temporary scratch-pad for conscious thou   (KRT Photos)
Turns out keeping your cool really is all in your head%u2014scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals.
Turns out keeping your cool really is all in your head%u2014scientists now pinpoint those most susceptible to stress as having too much of a chemical in a region of the brain that regulates reward signals.
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