Pharma Misbehaving

A popular diabetes drug may increase heart attack risks, a study reported in the New England Journal of Medicine concludes. Patients who took Avandia, which treats Type 2 diabetes, were 43% more likely to have a heart attack than those who took a placebo, the Cleveland Clinic study found. More »

The careless prescription of anti-psychotic drugs, often by psychiatrists who draw pay checks from the companies who make them, has drawn attention in the New York Times recently. Now Ann Bauer, writing in Salon , draws an intimate portrait of the effects of such carelessness on one autistic teenager, who turned from shy chess nerd to psychotic bruiser. More »

The company that makes OxyContin pleaded guilty today to misleading the public about the effects of the potent painkiller. Purdue Pharma and three executives will pay $634.5 million in civil and criminal fines. Federal prosecutors accused the firm of "misbranding" the drug, marketing it as a less addictive alternative to traditional pain meds although no evidence supported the claim. More »

The Times tackles the growing use of antipsychotic drugs in children, contentious because the drugs are risky and have no approved use for minors. But the trend is also questionable because it coincides with increasing payments to psychiatrists by the companies that market the drugs. In Minnesota, these payments rose sixfold from 2000 to 2005. More »

The Food and Drug Administration would be given sweeping new powers to order drug recalls, regulate advertising and mandate changes in labels under a bill passed by the Senate yesterday. The bill signals a fundamental shift in the FDA's role, the New York Times reports, requiring the agency to track drugs after, as well as before, approval. More »

Doctors are paid millions of dollars by drug companies to give their patients anemia medicine which regulators now say may be dangerous. Spurred by competiton between several similar drugs, companies reward doctors with rebates, which allow them to make a significant profit, the New York Times reports. More »

The drug-trafficking trial of a Virginia pain specialist demonstrates the slippery slope between treating chronic conditions and enabling addicts. Dr. William Hurwitz's jury heard the story of a patient with deblitating migraines who had been treated with anxiety medication that actually caused headaches—by another doctor who happened to be an expert  witness for the prosecution. More »

Pharma behemoth Merck is defending what it touted as a miracle cervical-cancer vaccine against charges of ineffectiveness. Merck lobbied states to mandate Gardasil for young girls—Texas and Virginia did—and got a glowing endorsement from the CDC. But new studies show that it works only to prevent sexually-transmitted HPV, a cause of cancerous cervical growths, not the cancer itself. More »

Ralph Moss writes about why inexpensive cancer treatments get no research dollars. The publisher of a newsletter that covers both conventional and alternative cancer therapies, Moss blames the inability to patent already discovered and available chemicals and drugs for the situation. More »

Shrinks are too quick to term patients clinically depressed, says a new study reported in the Washington Post . Researchers argue that a quarter of "acute grief reactions," the standard symptom of depression, may in fact constitute normal responses to stress; they blame the bloated psychopharmaceutical industry, in part, for the inaccurate triage. More »

Crusaders against performance enhancing drugs should lighten up about Human Growth Hormone: In the sports version of the war on drugs, anabolic steroids are heroin and HGH is marijuana, writes Daniel Engber. Studies haven't shown any definitive increase in athletic abilities resulting from taking HGH, and they have minimal harmful side effects. More »

Stents used to open arteries are no more useful than conventional drug treatment for patients who haven't yet had a heart attack, a new study reveals. In more than 2,000 patients over five years, those who had surgery suffered the same number of heart attacks, strokes, and deaths as those received only drugs. More »