CLEVELAND (AP) — U.S. Coast Guard crews were searching Lake Erie on Friday for a plane that went missing overnight shortly after takeoff from a small Cleveland airport along the shore.

The Columbus-bound Cessna Citation 525 departed Burke Lakefront Airport late Thursday night with six people aboard and disappeared from radar about 2 miles over the lake. Why remains unclear.

Searchers had found no sign of any debris or the people aboard the plane as of Friday morning, the agency said. Coast Guard official James Cox in Buffalo, New York, also said no emergency beacon had been detected.

Weather prevented a boat search overnight, but a U.S. Coast guard helicopter and a Canadian air crew in a plane were being used. A ship also was headed from Detroit to help with the search.

The waters in the search area are about 50 feet deep, the Coast Guard said.

The plane was headed to Ohio State University Airport northwest of downtown Columbus. Cox said the plane is kept at a hangar at the airfield, but the six people aboard the aircraft aren't affiliated with OSU. Their names weren't released, pending notification of their families.