ATHENS, Greece (AP) — Public services shut down across Greece Thursday as workers protested a new round of bailout-related tax hikes and spending cuts, in what is the first general strike since the country's left-led government initially came to power in January.

Public transport was severely disrupted. The Athens metro and suburban railway shut down while bus and trolley routes were reduced and ferries remained tied up in port, severing connections between islands and the mainland. More than a dozen domestic flights were also cancelled.

Nearly 25,000 people were marching through central Athens in three separate demonstrations, according to police figures. A march by a Communist-backed union gathered around 15,000 people, while 4,000 or so participated in a labor union demonstration and another 5,000 joined in a protest organized by anti-establishment and anarchist groups.

Another 10,000 marched through the country's second largest city of Thessaloniki.

The main party in the governing coalition — Prime Minister Alexis Tsipras' left-wing Syriza — showed sympathy towards the strikers. The party's department that deals with labor policy called for mass participation in the walk-out to protest "the neoliberal policies and the blackmail from financial and political centers within and outside Greece."

The strike closed museums, state schools and pharmacies, while state hospitals were functioning with emergency staff.

Journalists also walked off the job, pulling news bulletins off the air except to report on the strike. News websites were not being updated, while no Friday newspapers were to be printed. Lawyers, too, were scaling back their work.

Workers were protesting austerity measures imposed as part of Greece's third bailout — a three-year deal under which Greece will gradually receive up to 86 billion euros ($92 billion) in rescue loans from its partners in the 19-country eurozone in return for passing a raft of spending cuts and tax hikes.

Tsipras, who won re-election in September, signed up to the bailout in a dramatic policy change despite initially campaigning vigorously against bailouts and their accompanying austerity conditions. He has said he had no choice but to agree to the deal to prevent Greece from defaulting on its debts and being forced out of Europe's joint currency.

"I believe strikes can turn into a boomerang for the worker, but there are times when people need to react," said 61-year-old Yannis Nikolaidis as he marched in the protest near parliament. "This is the time when people need to react. Enough already with the taxes, enough with the double talk. They need to let us breathe."

The government is currently locked in negotiations to reach an agreement on the disbursement of a 2 billion-euro installment ($2.2 billion), as well as 10 billion euros set aside for the recapitalization of its banks.

While Greece has met many of the requirements, it remains at odds with creditors over how to deal with non-performing loans and the repossession of homes whose owners have fallen into arrears on mortgage payments.

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Costas Kantouris in Thessaloniki contributed.