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Scientists: We Can Destroy 'Aging Cells'

Study targeted mouse senescent cells, responsible for many aging effects

By Mark Russell,  Newser Staff

Posted Nov 3, 2011 4:55 AM CDT

(Newser) – It's not the fountain of youth ... yet. But scientists think they have taken a major step toward staving off some of the conditions of aging by removing senescent cells—cells that have stopped dividing—from mice, reports the Wall Street Journal. In the study, rapidly aged mice were given a drug designed to destroy senescent cells, resulting in a "quite dramatic delay" in the development of many age-related diseases, muscle-wasting—and wrinkles.

While senescent cells comprise less than 5% of cells, even in the elderly, they produce harmful compounds that cause inflammation, thought to be the underlying cause of many age-related diseases, such as cataracts, arthritis, and dementia. But because senescent cells also spur the immune system and suppress cancers, scientists were not sure if their benefits outweighed their harmful qualities. "If you could clear senescent cells, you perhaps could treat age-related diseases as a group rather than individually," said the paper's lead author. You can check out the abstract of the original article in Nature.

By eliminating senescent cells from mice, scientists say they've taken a major step in combating the harmful effects of aging.
By eliminating senescent cells from mice, scientists say they've taken a major step in combating the harmful effects of aging.   (Shutterstock)
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COMMENTS
Showing 3 of 15 comments
JoeQ
Nov 3, 2011 3:45 PM CDT
It'll make a great skin cream for late night infomercials.
jimg
Nov 3, 2011 3:29 PM CDT
This will cost a metric ton.
Chitrix
Nov 3, 2011 8:19 AM CDT
"But because senescent cells also spur the immune system and suppress cancers, scientists were not sure if their benefits outweighed their harmful qualities." And thus the truth of it all, cure one thing and enhance 1 billion others................... We all die, get over it and let it ride.................................................................... Its call live, get on with it and get it over....... Besides, if you lived forever imagine how tired you would become of the politics Just sayin
 

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