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Worries Dog HIV-Blocking Little Blue Pill

Truvada could create drug-resistant HIV strain

By Neal Colgrass,  Newser Staff

Posted May 14, 2012 5:10 PM CDT

(Newser) – A drug designed to block HIV infection comes with a little hitch: Used incorrectly, it could invite infection or create a resistant strain that renders the drug useless. The very FDA panel that recommended approval for the drug, Truvada, tangled with these dilemmas, the New York Times reports: What if people at risk of contracting HIV take Truvada intermittently—even as an occasional party drug—and contract the disease? And what if a drug-resistant strain emerges?

The other side called such worries paternalistic, and argued for giving people a powerful tool to protect themselves—even though one major study showed that only 10% of Truvada users stuck to their daily regimen. And side effects like initial stomach upset make Truvada even harder to stick with. But the FDA typically follows its panel's advice, the Times notes, so Truvada should soon be available for those who need it—like gay men with multiple partners, prostitutes, and people in relationships with HIV-positive partners.

This May 26, 2006, file photo, shows a close up of Gilead Sciences Inc.'s Truvada pill in a lab in a Foster City, Calif.
This May 26, 2006, file photo, shows a close up of Gilead Sciences Inc.'s Truvada pill in a lab in a Foster City, Calif.   (AP Photo/Paul Sakuma, File)
In this Thursday, May 10, 2012, photo, Dr. Lisa Sterman holds up a Truvada pill at her office in San Francisco.
In this Thursday, May 10, 2012, photo, Dr. Lisa Sterman holds up a Truvada pill at her office in San Francisco.   (AP Photo/Jeff Chiu)
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COMMENTS
Showing 3 of 10 comments
StationaryMan
May 15, 2012 2:03 PM CDT
There is another worry, the pill costs $36 a piece, exactly who will be paying for them? Prostitutes?  And wont this pill just foster unsafe sex? Did they test the partners of the volunteers to find out if HIV spread through the one taking the pill even though it protected him/her? Although I guess the drug company just wants the entire population to start taking the pill.
Riffran
May 15, 2012 4:37 AM CDT
my dogs are spayed...no worries 
fractal
May 15, 2012 2:40 AM CDT
It is not paternalistic to worry about drug resistance and the compliance of users.  It is human nature to be in denial of the long range dangers of ANYTHING.  We just evolved to be concerned with immediate dangers, like claws in your face. And this flaw may be our species downfall.
 

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