Ohio Killer to Be Executed With Method Untested in US Dennis McGuire will be put to death using 2-drug combination By Newser Editors and Wire Services Posted Jan 1, 2014 10:44 AM CST 45 comments Comments This undated file photo provided by the Ohio Department of Rehabilitation and Correction shows Dennis McGuire. (Uncredited) (Newser) – Ohio will use a dose of two drugs untried in the US to put to death a condemned inmate who raped and killed a pregnant woman, according to a decision by the state prison system. The determination means the prisons agency was unable to obtain an unregulated batch of pentobarbital, the drug Ohio used until its manufacturer put it off limits for executions. Instead, the state will use drugs from its untested backup execution method in the Jan. 16 execution of Dennis McGuire, according to the decision contained in a memo by Southern Ohio Correctional Facility warden Donald Morgan released to the AP after a public records request. The untested method: an intravenous combination of midazolam, a sedative, and hydromorphone, a painkiller. No state has put a prisoner to death with those drugs in any fashion. The drugs were part of a backup method in which they would be injected into an inmate's muscle if the intravenous method failed. Because the pentobarbital is unavailable, this two-drug combination will be the primary method for execution and injected into McGuire's veins. McGuire, 53, of Preble County in western Ohio, was sentenced to death for killing Joy Stewart in 1989 after meeting her while working on her friend's house. Investigators say McGuire raped and choked the 22-year-old Stewart and stabbed her in the neck and shoulder. Stewart was about eight months pregnant.