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Drug Therapy Cuts Risk of Breast Cancer Relapse

Aromatase inhibitors work after tamoxifen regimen ends

By Rob Quinn,  Newser Staff

Posted Mar 11, 2008 7:16 AM CDT

(Newser) – New research shows that women can cut the risk of breast cancer recurring years later by taking certain drugs, the Washington Post reports. Studies show that the drugs, known as aromatase inhibitors, sharply reduced the risk of cancer's return after women had finished their regimen of the widely used tamoxifen. The findings could dramatically change the treatments breast cancer survivors are given.

Tamoxifen, an estrogen blocker, reduces the risk of breast cancer returning, but it loses effectiveness and raises other health risks after five years. "What is important for doctors and patients to recognize unfortunately is that the risk of recurrence of this type of breast cancer does not end at five years," a researcher told Reuters. Aromatase inhibitors cut the cancer risk even in women who had ceased taking tamoxifen 7 years earlier.

The new research shows there is a need for a paradigm shift in treating breast cancer survivors, Nancy U. Lin and Eric P. Winer of the Dana-Farber Cancer Institute wrote in an editorial that accompanied the findings that drugs can reduce the risk of breast cancer returning.
The new research shows there is a need for a "paradigm shift" in treating breast cancer survivors, Nancy U. Lin and Eric P. Winer of the Dana-Farber Cancer Institute wrote in an editorial that accompanied...   ((c) patti haskins)
Texas coach Rick Barnes, wearing a pink tie, watches during the first half of a college basketball game against Iowa State, Saturday, Feb. 9, 2008, in Ames, Iowa. Many men and women basketball teams are wearing pink in a national effort to raise breast cancer awareness. (AP Photo/Charlie Neibergall)
Texas coach Rick Barnes, wearing a pink tie, watches during the first half of a college basketball game against Iowa State, Saturday, Feb. 9, 2008, in Ames, Iowa. Many men and women basketball teams are...   (Associated Press)
New studies published today found that women can dramatically reduce the risk of breast cancer reoccuring with the use of drugs known as aromatase inhibitors.
New studies published today found that women can dramatically reduce the risk of breast cancer reoccuring with the use of drugs known as aromatase inhibitors.   ((c) Aine D)
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