Top 5 Causes of Death for Men, Women Heart disease, cancer top both lists By Arden Dier, Newser Staff Posted Jun 30, 2016 11:14 AM CDT 34 comments Comments Heart disease is deadliest for both. (Shutterstock) (Newser) – Alzheimer's deaths are on the rise, according to the most recent data. An analysis of all US death certificates from 2014 shows deaths related to Alzheimer's spiked 10.5% over 2013, per the Los Angeles Times. Such deaths still make up just 5% of deaths for women and 2.2% for men, however. Leading the way in terms of causes of death were the usual villains of heart disease (23.4%) and cancer (22.5%). The leading causes of death differ for men and women: For men: Heart disease Cancer Accidents Respiratory diseases Stroke For women: Heart disease Cancer Respiratory diseases Stroke Alzheimer's Click for the top 10 causes of death overall or a list of American fears.