Serious Side Effects Linked to Avandia, Fosamax

Heart trouble, brittle bones tied to drugs
By Peter Fearon,  Newser Staff
Posted Apr 29, 2008 2:57 AM CDT
GlaxoSmithKline's drug Avandia, prescribed for diabetes, has been linked to fractured limbs.    ((c) Ian Wilson)
camera-icon View 2 more images

(Newser) – Two new studies have linked the popular prescription drugs Fosamax and Avandia to serious side effects, Reuters reports. Fosamax, prescribed for osteoporosis, has been tied to a type of abnormal heartbeat that can cause dizziness and fatigue. Another study links Avandia, used to treat diabetes, to a double or even triple risk of broken limbs after long-term use.

Fosamax maker Merck said in a statement that the company's own clinical trial did not find a statistically significant link between an abnormal heartbeat and Fosamax.  "We strongly recommend that if patients have concerns about Fosamax they talk to their physician," the statement added.