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TUESDAY, NOVEMBER 24, 2009
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Cancer Vaccine Shows Promise

Colorectal disease spreads more slowly in immunized mice

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(Newser) – Encouraging results in experiments on mice are raising hopes of an effective colon cancer vaccine, Reuters reports. Capitalizing on the fact that the intestines have their own immune system, researchers isolated a protein that occurs only in the gut to create a vaccine. In treated mice, an average of three tumors appeared in the lungs or liver. In unvaccinated mice, the number was 30.

"We think this identifies a novel class of vaccine candidate targets for tumors that originate and metastasize from mucosa, like colorectal cancer," wrote the lead researcher.

A flu shot is administered. Researchers have taken a step toward developing a vaccine for colorectal cancer.
A flu shot is administered. Researchers have taken a step toward developing a vaccine for colorectal cancer.   (AP Photo/Toby Talbot)
A nurse fills a syringe with flu vaccine at the Arkansas State Fair Grounds. Scientists say a vaccine for colon cancer may be possible in the future.
A nurse fills a syringe with flu vaccine at the Arkansas State Fair Grounds. Scientists say a vaccine for colon cancer may be possible in the future.   (AP Photo/Danny Johnston)
Dr. William Taylor, medical director of colorectal surgical oncology for the John B. Amos Cancer Center, looks over scans in his office in Columbus, Ga.
Dr. William Taylor, medical director of colorectal surgical oncology for the John B. Amos Cancer Center, looks over scans in his office in Columbus, Ga.   (KRT Photos)
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