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WEDNESDAY, NOVEMBER 25, 2009
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9

Decoding of Genome Fails to Yield Promised Cures

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(Newser) – The promised age of unlocking the mystery of common diseases through DNA appears to have a hit a disappointing roadblock, the New York Times reports. As a result, companies that bill people to provide a personal genomic profile—and theoretically warn them of their risk to illness—are practicing nothing more than "recreational genomics," a geneticist tells the Times. “The information has little or in many cases no clinical relevance.”

In a series of essays in the New England Journal of Medicine, the Duke geneticist and others in the field wrestle with the disappointing reality—that the decoding of the human genome in 2003 has done relatively little to explain genetic links to most diseases. The essays appear to be the first public attempt to deal with the problem and debate whether the current strategy—called genomewide association study—needs to be scrapped or revised, the Times notes.

Scientists say the decoding of the human genome hasn't yielded the expected medical breakthroughs.
Scientists say the decoding of the human genome hasn't yielded the expected medical breakthroughs.   (Shutter Stock)
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Nagual
Apr 15, 09 11:31 PM CDT
It's been apparent for some time now that it needs to be revised; only now is it becoming accepted in the mainstream scientific community, unfortunately. Reply
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Mad
Apr 15, 09 11:42 PM CDT
This is sad news. All the hope and promise that de-coding the Human Genome seemed to bring is proving to be more elusive than we initially thought. Damn. Reply
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TerrifiedCitizen
Apr 16, 09 12:52 AM CDT
Often, studies like this are pigeon-holed or abandoned only to be rediscovered later as the result of another study that illuminates a missed connection... perhaps this will mean more to us in the future when we have progressed. Reply
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riffran
Apr 16, 09 2:16 AM CDT
It's probably a case of not seeing the forest through the trees. It's one thing to decode the sequences, but another thing altogether to actually make sense of it...sort of like breaking down a computer program into pages of straight binary...and having a non programmer go through it Reply
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Rob
Apr 16, 09 5:42 AM CDT
This statement is overly pessimistic. Genetic research has progressed and advancements are obvious. Have we unlocked a panacea? Maybe not. Have we realized some amazing advancements in genetic applications? Hell yes. Reply
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