Scientists Unveil Male Pill And guys only have to remember to take it 4 times a year By Kate Seamons, Newser Staff Posted Jun 28, 2010 6:42 AM CDT 52 comments Comments The male version is just one pill every three months. (©outcast104) (Newser) – Scientists say they've finally created the "male pill"—and it sounds pretty easy to swallow. Developed by researchers in Israel, the oral pill works by removing a crucial protein in sperm, effectively deactivating it before it reaches the womb. It's proven to be 100% effective—at least on mice. And that's not the only impressive upside. The pill only has to be taken once every three months, and reportedly has no impact on male sex drive or other side effects. Human trials begin next year; the pill could be available in three years, reports the Telegraph.