lab mice

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Scientists Make Shrunken, See-Through Lab Mice

'We can look into the wiring of the whole mouse in high resolution'

(Newser) - If your initial reaction is one of queasiness, it would be understandable: A new technique announced Monday in Nature Methods essentially allows scientists to make dead mice see-through—by stripping the lipids and water from the animals' tissues. The fat is what makes the tissues opaque; the removal of water... More »

Cinnamon Might Make Us Better Learners

Mice who ate cinnamon showed improved memory, learning

(Newser) - Scientists say they've discovered "one of the safest and the easiest approaches to convert poor learners to good learners." And all you have to do is eat cinnamon. Researchers at Rush University Medical Center say that feeding cinnamon to mice with a poor learning ability turned them... More »

Scientists Turn Bad Memories to Happy Ones

Research could mean more effective treatment for human disorders

(Newser) - Scared to death of spiders after you found one crawling in your bed? Scientists may have discovered a way for you to find them positively cuddly. After identifying the neurons powered by positive and negative memories in mice, MIT neuroscientists found a way to use light to essentially rewrite a... More »

Lack of Sleep Can Fry 25% of Brain Cells

Study of mice finds brain damage with prolonged sleep loss

(Newser) - A lack of shut-eye may not just leave you feeling groggy—it could seriously injure your brain. A new study of mice has found 25% of brain cells died off after prolonged sleep loss, meant to duplicate night shifts or long hours at the office—the first evidence of its... More »

Fried, Grilled Meat Linked to Dementia Risk

Compound caused memory loss in mice

(Newser) - Does frying meat end up frying your brain? Researchers working with lab mice have discovered that a diet high in a compound created when meat is fried or grilled caused them to have memory loss and other problems associated with Alzheimer's disease, reports the BBC . The advanced glycation end... More »

Down Syndrome 'Reversed' in Mice

Researchers were able to affect the growth of the cerebellum

(Newser) - We'll start by tempering expectations: The breakthrough you're about to read about has "no direct link" to a human treatment, reports AFP , but it's noteworthy nonetheless. Scientists say they've identified a molecule that "reverses" the effects of Down syndrome in mice. The molecule is... More »

Is Young Blood the Fountain of Youth?

Young blood reverses some brain aging in old mice

(Newser) - Vampires have known; now research mice are beginning to learn. Experiments on mice have shown that it's possible to rejuvenate animals by giving them blood from the young, according to a Standford University study. Blood from young mice reversed some of the effects of brain aging, improving learning and... More »

Lab-Made Eggs Produce Healthy Mice

Points way to human infertility treatments

(Newser) - A year back, scientists in Japan produced healthy mice from lab-created sperm ; now, they've done the same with lab-made eggs. The project has big implications for humans, potentially paving the way for infertile men and women to have their own offspring. "This is quite a startling feat,"... More »

Ailing? Maybe Your 'Mini-Me' Mouse Can Help

Doctors implant your disease into mice to hone treatment

(Newser) - The New York Times says it "could be the ultimate in personalized medicine," and it's hard to disagree. The idea is to give mice the same disease you have—as in, implant part of your tumor into the rodents—to help doctors zero in on a precise... More »

'Signal Sending' Glasses Could Restore Lost Vision

Technology helps blind mice see

(Newser) - More good news for the estimated 20 million people who have lost or will lose their eyesight worldwide. Researchers have found a way to restore lost vision in mice, and they say the same technology can likely be developed for humans within two years, pending funding, reports Bloomberg . Scientists focused... More »

Baldness Cure Discovered by Accident?

Single jab reversed hair loss in lab mice

(Newser) - Researchers studying stress hormones were surprised to stumble upon what appears to be a cure for baldness—at least in mice. Mice who had gone bald due to overproduction of a stress hormone were treated with a compound that blocks stress in the gut and then returned to cages where... More »

Scientists Reverse Aging in Mice

Could the process work for humans?

(Newser) - Harvard scientists have reversed the aging process in mice, injecting them with an enzyme that healed tissue and reportedly spurred the growth of new neurons in their brains. Now they’re wondering if they can apply some of these benefits to humans. But differences between human and mice bodies make... More »

Caffeine Won't Actually Make You Sober

And combo with booze may breed dangerous overconfidence

(Newser) - Caffeine doesn't sober you up, but it does make you feel less drunk, and that combination could have dangerous consequences, a new study suggests. Researchers came to the conclusion after giving mice alcohol and caffeine, together and separately, and comparing how they navigated a tricky maze, reports Scientific American . More »

Nighttime Snacks Worse Than We Thought

Mouse study shows weight gain more than doubles on opposite schedule

(Newser) - Eating when you should be sleeping—the proverbial midnight snack, say, or the meals of night-shift workers—could put you at higher risk of obesity, Time reports. A new study fed two groups of mice the same high-fat diet on opposite schedules; the group that ate during “normal” waking... More »

Scientists Breed Mice From Stem Cell Alternative

Researchers turn adult, not embryonic, skin cells into stem cells

(Newser) - Scientists in China have created mice using stem cells made from modified skin cells—hinting at an alternative to embryonic stem cells, the Washington Post reports. Separate teams used viruses to manipulate genes that caused mice skin cells to regress back into induced pluripotent stem cells—which, within a placenta... More »

Pill May Slash Body Weight By a Quarter

Combination of hormones has a potent effect on mice

(Newser) - A drug that cut the body weight of mice by 25% is raising hopes for humans, the Daily Telegraph reports. The rodents lost 42% of their fat mass after a week, with even more powerful effects seen over a month. The pill combines hormones that have been found to weaken... More »

Rodent Rights Activists Face Uphill Climb

Animal campaigners seek a better quality of life for lab rats

(Newser) - Activists have managed to improve the lives of many animals in recent years, but they've met indifference when it comes to getting a better deal for rodents, the Wall Street Journal reports. Rats and mice make up 90% of the animals used in research in the US, say advocates, but... More »

Stem Cells Zap Infertility in Female Mice

Researchers believe treatment could reverse human menopause

(Newser) - Chinese scientists say they have reversed infertility in female mice by creating new eggs from stem cells, the Independent reports. The research—which if it bears out could have heady implications for reproductive medicine, including reversing menopause—took stem cells from the ovaries of mice, cultivated them, and transplanted them... More »

Parkinson's Treatment Shows Promise in Mice

(Newser) - Potential good news for Parkinson's patients: An experimental treatment on mice that involves implanting electrodes on the spinal cord had great success, Reuters reports. Mice that received the so-called stimulator were able to move more easily. Human trials are expected to start next year, and they could lead the way... More »

Genetic Therapy Reverses Heart Disease in Mice

Trials in other animals have begun; humans would be up next

(Newser) - Damage to heart muscle can be stopped and maybe even reversed, but for now only in mice, the BBC reports. Blocking the activity of a specific type of genetic material that regulates gene expression, scientists found, avoided a type of cardiac scarring that leads to heart disease. "Heart function... More »

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