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Cold Sore Drugs Could Treat Alzheimer's

By Harry Kimball, Newser Staff

Posted Dec 6, 2008 4:13 PM CST

(Newser) – British researchers have firmed up a link between cold sores and Alzheimer's disease, the Times of London reports. The virus behind the sores apparently helped cause Alzheimer's in 60% of cases studied, which may mean that common antiviral drugs can stop the disease. “If we are right, there is a good chance we could make progress quite quickly,” the lead researcher said.

The University of Manchester group showed that the virus, HSV1, infected protein plaques in the brain cells of Alzheimer's sufferers. Now the question is whether the virus infects while active—when antiviral drugs would be effective—or during a latency period. The researchers are seeking funding for animal tests but have so far been turned down.

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An Alzheimer's sufferer. (AP Photo)

Alzheimer's patient Dorothy Eckert, left, hugs her daughter Louise Eckert at their home in Norristown Pa. (AP Photo)

MRI pictures show quantified brain structures of a healthy person and a patient with Alzheimer's disease. (AP Photo)

French President Nicolas Sarkozy looks through a microscope as he visits the Institute of Molecular and Cellular Pharmacology, in support of the battle against Alzheimer's Disease. (AP Photo)

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Antiviral agents would inhibit a likely major cause of the disease irrespective of the damaging processes involved, whereas current treatments at best merely inhibit some of the symptoms. - Matthew Wozniak, Alzheimer's researcher

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