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For HIV, Women the Weaker Sex

Hormone leads to higher immune activity, faster progression

By Evann Gastaldo,  Newser Staff

Posted Jul 14, 2009 12:00 PM CDT

(Newser) – Women may be the weaker sex when it comes to HIV. The virus progresses faster in women, and a new study published in Nature Medicine finds that may be due to the hormone progesterone, the BBC reports. The research team is continuing work on the findings to see if they can develop a drug to slow or stop HIV’s progression to AIDS.

The study found that women’s immune cells were more active when first presented with the virus than men’s, but post-menopausal women—who have lower levels of progesterone—had responses similar to men. Though the immune activity can be beneficial at first, “stronger chronic immune activation can lead to the faster progression of AIDS that has been seen in women,” the lead researcher says.

In this May 7, 2009 photo, Michelline Leon, a woman living with HIV/AIDS, poses for a photo with her children in Cange, in central Haiti.
In this May 7, 2009 photo, Michelline Leon, a woman living with HIV/AIDS, poses for a photo with her children in Cange, in central Haiti.   (AP Photo/Ramon Espinosa)
A nurse takes a blood sample from a woman during a national HIV testing campaign in San Salvador, Friday, June 26, 2009.
A nurse takes a blood sample from a woman during a national HIV testing campaign in San Salvador, Friday, June 26, 2009.   (AP Photo/Luis Romero)
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Whilst there are some genetic differences based on sex, access to treatment remains the single most important factor in preventing HIV from progressing to AIDS.
- Jo Robinson of Terrence Higgins Trust

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COMMENTS
Showing 1 of 1 comment
kokuaguy
Jul 14, 2009 7:10 AM CDT
Have you read "Running with Scissors? "

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