lab mice

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Nighttime Snacks Worse Than We Thought

Mouse study shows weight gain more than doubles on opposite schedule

(Newser) - Eating when you should be sleeping—the proverbial midnight snack, say, or the meals of night-shift workers—could put you at higher risk of obesity, Time reports. A new study fed two groups of mice the same high-fat diet on opposite schedules; the group that ate during “normal” waking...

Scientists Breed Mice From Stem Cell Alternative

Researchers turn adult, not embryonic, skin cells into stem cells

(Newser) - Scientists in China have created mice using stem cells made from modified skin cells—hinting at an alternative to embryonic stem cells, the Washington Post reports. Separate teams used viruses to manipulate genes that caused mice skin cells to regress back into induced pluripotent stem cells—which, within a placenta...

Pill May Slash Body Weight By a Quarter

Combination of hormones has a potent effect on mice

(Newser) - A drug that cut the body weight of mice by 25% is raising hopes for humans, the Daily Telegraph reports. The rodents lost 42% of their fat mass after a week, with even more powerful effects seen over a month. The pill combines hormones that have been found to weaken...

Rodent Rights Activists Face Uphill Climb

Animal campaigners seek a better quality of life for lab rats

(Newser) - Activists have managed to improve the lives of many animals in recent years, but they've met indifference when it comes to getting a better deal for rodents, the Wall Street Journal reports. Rats and mice make up 90% of the animals used in research in the US, say advocates, but...

Stem Cells Zap Infertility in Female Mice

Researchers believe treatment could reverse human menopause

(Newser) - Chinese scientists say they have reversed infertility in female mice by creating new eggs from stem cells, the Independent reports. The research—which if it bears out could have heady implications for reproductive medicine, including reversing menopause—took stem cells from the ovaries of mice, cultivated them, and transplanted them...

Parkinson's Treatment Shows Promise in Mice

(Newser) - Potential good news for Parkinson's patients: An experimental treatment on mice that involves implanting electrodes on the spinal cord had great success, Reuters reports. Mice that received the so-called stimulator were able to move more easily. Human trials are expected to start next year, and they could lead the way...

Genetic Therapy Reverses Heart Disease in Mice

Trials in other animals have begun; humans would be up next

(Newser) - Damage to heart muscle can be stopped and maybe even reversed, but for now only in mice, the BBC reports. Blocking the activity of a specific type of genetic material that regulates gene expression, scientists found, avoided a type of cardiac scarring that leads to heart disease. "Heart function...

Leukemia Drugs Cure Mouse Diabetes
Leukemia Drugs Cure Mouse Diabetes
Nov 18, 2008 5:37 AM CST

Leukemia Drugs Cure Mouse Diabetes

Common cancer treatment sent disease into rapid remission

(Newser) - Two common leukemia drugs prevented or halted mouse diabetes in a new study, Reuters reports. The drugs prevented mice predisposed to Type 1 diabetes from developing the disease, and sent 80% of mice who already had it into remission within weeks. Scientists say the mice maintained normal blood sugar levels...

Scientists Wipe Mouse Memories

Treatment selectively erased memories of electric shocks

(Newser) - Scientists have succeeded in blanking selected memories from the brains of mice, Reuters reports. After brain protein levels were manipulated, the mice lost the memory of an electric shock but didn't forget anything else. The researchers said it was doubtful that it would be possible—or desirable—to do the...

Guzzle Coffee, Prevent Multiple Sclerosis?

Mice who consumed equivalent of 6-8 cups a day were protected

(Newser) - For preventing the autoimmune disease multiple sclerosis, caffeine might be just what the doctor ordered, the Daily Telegraph reports. In a study involving what must have been some very jittery mice, researchers found that the equivalent of 6-8 cups of coffee per day conferred protection from the rodent equivalent of...

Cancer Vaccine Shows Promise
 Cancer Vaccine Shows Promise 
Jun 24, 2008 5:11 PM CDT

Cancer Vaccine Shows Promise

Colorectal disease spreads more slowly in immunized mice

(Newser) - Encouraging results in experiments on mice are raising hopes of an effective colon cancer vaccine, Reuters reports. Capitalizing on the fact that the intestines have their own immune system, researchers isolated a protein that occurs only in the gut to create a vaccine. In treated mice, an average of three...

Cloned Stem Cells Best for Parkinson's

Study finds mice's own stem cells most effective vs disease

(Newser) - Scientists have found that embryonic stem cells effectively treat Parkinson's disease in lab mice, but only when the cells come from the sick mouse's own clones, Reuters reports. The study, published in Nature Medicine, created "therapeutic clones" by transferring cell nuclei into mouse egg cells and growing them into...

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